Hematological indices and abnormalities among patients with uncomplicated falciparum malaria in Kosti city of the White Nile state, Sudan: a comparative study

Abstract Background Hematological abnormalities are common features in falciparum malaria but vary among different populations across countries. Therefore, we compared hematological indices and between Plasmodium -infected patients malaria-negative subjects Kosti city of the White Nile State, Sudan. Methods A comparative, cross-sectional study was conducted at Clinical Laboratory Unit Teaching Hospital from June to December 2018. total 392 participants (192 P. 200 subjects) were recruited study. hemoglobin (Hb), red blood cells (RBCs), white (WBCs) platelets measured, their median values statistically compared. Results The majority (67.6%) showed a low-level parasitemia. Hb concentration, RBC count, mean corpuscular volume (MCV), (MCH) concentration (MCHC) significantly lower patients, while cell distribution width (RDW) higher subjects. Anemia, low MCV, MCH, MCHC high RDW associated with malaria, parasitemia level not anemia severity. WBC count non-significantly neutropenia being malaria. platelet thrombocytopenia Conclusions Falciparum Sudan is predominantly It anemia, MCHC, RDW, neutropenia. However, significant predictor On other hand, leucopenia useful predict Further large-scale studies community healthcare settings inclusion complicated or severe those parasite densities recommended.